Archive for September 25th, 2012

Oxime formation from hydroxylamine and ketone. Part 2: Elimination.

Tuesday, September 25th, 2012

This is the follow-up to the previous post exploring a typical nucleophilic addition-elimination reaction. Here is the elimination step, which as before requires proton transfers. We again adopt a cyclic mechanism to try to avoid the build up of charge separation during those proton movements.

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