Archive for February 20th, 2012

E2 elimination vs ring contraction: anti-periplanarity in action.

Monday, February 20th, 2012

The anti-periplanar principle permeates organic reactivity. Here I pick up on an example of the antiperiplanar E2 elimination (below, blue) by comparing it to a competing reaction involving a [1,2] antiperiplanar migration (red). (more…)