|[Related articles/posters: 120 103 024 ]|
We are investigating the mechanism of PBG-synthase by active site directed inhibition studies. The procedure for testing and the data obtained with compounds related to 4,6-dioxoheptanoic acid (1) are reported and the results are discussed in the context of our kinetic model.
***conclusion ***literature*** synthesis***
Synthesis of other inhibitors of PBGS