Halogen Dance techniques as well as their selective preventions developed for the first time within our research group
have been proven to be useful and versatile synthetic methods to access a whole host of novel multi-substituted thiophenes
and furans , . Some examples thereof have already been displayed during ECHET96 by our group
, , . Extension to bromo-bithiophenes allowed selective mono and double halogen migration.
Moreover, butyl lithium induced ring opening reactions on specifically designed model substrates led to novel conjugated en-ynes.
Within this lecture transfer of this methodology to hetero biaryls extended through aryl, hetaryl and alkynyl spacers will be presented.