Experiment 6, page 2

Ozonisation is effected by passing a stream of dry ozonised oxygen (1–15% O3) through a solution
of the olefin in a suitable solvent (AcOH, CCl4,CHCl3, hexane, EtOAc are all used) at or below

room temperature until the ozone is no longer rapidly absorbed. Over ozonisation will cause
general oxidation and decomposition.

HAZARD DATA - READ THIS BEFORE GOING ANY FURTHER!!!!

OZONE:
VERY TOXIC BY INHALATION
SKIN/EYE IRRITANT
EXPLOSIVE WITH REDUCING AGENTS
A toxic gas which forms explosive ozonides with many olefins. Avoid inhalation and skin/ eye contact. OEL 0.2
mgm-3.

Toxic effects:

Gas strongly irritates the upper respiratory tract and may cause headache. High
concentrations have caused death by lung congestion in animals. Harmful by skin
contact.
Solid and liquid ozone are highly explosive; forms explosive peroxides with alkenes and
other organic molecules. Explodes with many reducing agents; Br2, HBr, N2O4.

Hazardous reactions:

ACETIC ACID:

FLAMMABLE
CAUSES SEVERE BURNS

Colourless liquid, with acrid pungent odour; b.p. 118ºC, m.p. 17ºC. Soluble in water. OEL 25mgm-3

Toxic effects:

Causes severe burns. Causes internal irritation and damage if taken by mouth. Irritiating
vapour.
Dangerous in contact with chromic acid, sodium peroxide, and nitric acid. Causes
vigourous exothermic polymerisation with acetaldehyde.
Wash areas with water and then ventilate to dispel residues.

Hazardous reactions:

Spillage & disposal: