Re: Poster No 30 (Ray Jones)

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Tue, 20 Jun 1995 15:51:14 +0000

Forwarded on behalf of Simon Ellwood
Dear Ray,
Having read your poster I have a couple of points I would
like to make:

1. You say that epimerisation of 3 occurs to give epi-3 in the text
but the scheme shows structure 2, is this correct?

2. Prompted by 1. can you get compound 2 to epimerise under forced
conditions (relative to compd 3)?. If not then it seem to me that the
stereochemistry of the nitrile containing carbon must be important wrt
the mechanism (although I cannot see why).

Simon Ellwood

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