Enantiopure or enantioenriched (scalemic) molecules
- The first scalemic molecule with its absolute configuration determined was Rubidium tartrate
- ... A (single) crystal may not represent what a solution contains ...
- 585,235 sets of coordinates (CCDC) crystal database
- of which 98,424 are in Chiral space groups
- 82,937 (no disorder/error)
- 24,482 ≤ 200K (those with the most accurate data)
- ~81% report a value for the Flack Parameter (1983) for enantiomorph estimation
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- ~11,851 (of the 24,482) are classed as statistically meaningfull
- but which do not distinguish between:
- conformational chirality (low dynamic stability)
- configurational chirality (high dynamic stability)
- ... A (single) crystal may not represent what a solution contains!