References

[1a]  http://pubs.acs.org/hotartcl/ac/97/jun/mol.html
[1b] Steinke, J.; Sherrington, D.C.; Dunkin, I.R. Imprinting of Synthetic Polymers Using Molecular Templates Adv. Polymer Science Vol. 123, 81-125 (1995).
[1c] Wulff, G. Angew. Chem. 107, 1958-1979 (1995).

[2] see e.g. US5461175 "Method for separating enantiomers of aryloxipropanolamine derivatives, and chiral solid-phase chromatography material for use in the method". This patent is available in the net e.g. via http://qpat2.qpat.com

[3]    Acetone was also used for the removal of the fines via sedimentation, but acetonitrile gave better results as here the fines settled two times slower than in acetone.

[4] The details of the chiral CE-separation of galanthamine will be published elsewhere

[5] Bores, G.M.; Kosley, R.W. Galanthamine Derivatives for the Treatment of Alzheimer's Disease, Drugs of the Future, 1996, 21, 621-635.

[ 6 ]  Czollner, L.; Frantsits, W.; KŸenburg, B.; Hedenig, U.; Fršhlich, J.; Jordis, U. "New Kilogram-Synthesis of the Anti-Alzheimer Drug (-)-Galanthamine" Tetrahedron Letters 1998, 39, 2087-2088.