Synthesis of heterocycle-annelated naphthyridones with a bridgehead nitrogen atom


Synthesis of [g]-fused [1,6]naphthyridones

When ethyl 2-chloronicotinoate (16) [8] was employed as the starting material, the [g]-fused [1,6]-naphthyridones 14-17 were obtained [9]. (1d).

Scheme 3

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