Recent Publications

PDF-files of some the articles (to view use Acrobat Reader) are available via the journal homepage.

A Short Efficient Route to C2 Symmetric 1,1',2,2'-Tetrasubstituted Ferrocenes. M. A. Carroll, D. A. Widdowson and D. J. Williams, Synlett, 1994, 1025 - 1026.

Electrophilic Fluorination in the Synthesis of New Fluoroindoles. Harold F. Hudson, David J. Madge, Alexandra M.Z. Slawin, David A. Widdowson and David J. Williams, Tetrahedron, 1994,< b>50, 1899-1906.

A New Facile Synthesis of S-Trifluoromethyldibenzo[b,d]thiophenonium trifluoromethanesulfonate (TDTT). Sean S. Aiken, Julia A.H. Lainton and David A. Widdowson Electronic Conference on Trends in Organic Chemistry 1995, (ECTOC-1), Eds H.S. Rzepa and J. M. Goodman (CD-ROM), RSC Publications)

Synthetic Applications of Arenetricarbonylchromium(0) Complexes: The Synthesis of Polyfunctionalised Thiophenes. Michael S. Loft, Timothy J. Mowlem and David A. Widdowson, J. Chem. Soc., Perkin Trans. 1, 1995, 97 - 103.

Enhanced Lability of Silyl Groups in Thiophenetricarbonylchromium(0) Complexes. Michael S. Loft , Timothy J. Mowlem , David A. Widdowson and David J. Williams, J. Chem. Soc., Perkin Trans. 1, 1995, 105 - 109.

The Synthesis of Precisely Structured Polyurethanes 1: Monomer Synthesis. Alistair A. Denholm, Maurice H. George, Helen C. Hailes, Peter J. Tiffin and David A. Widdowson, J. Chem. Soc., Perkin Trans. 1, 1995, 541 - 547.

Synthetic Applications of Biotransformations: Absolute Stereochemistry and Diels-Alder Reactions of the 2-Dihydroxycyclohexa-3,5-dienecarboxylic Acid from Pseudomonas putida U103. Gareth N. Jenkins, Douglas W. Ribbons, David A. Widdowson, Alexandra M.Z. Slawin and David J. Williams, J. Chem. Soc., Perkin Trans. 1,  1995, 2647 - 2655.

Regiospecific Synthesis of 4-Fluoro-3-ketosteroids using  Caesium Fluoroxysulfate. Harold F. Hodson, David J. Madge and David A. Widdowson, J. Chem. Soc., Perkin Trans. 1,  1995, 2965 - 2968.

The Synthesis of Precisely Structured Polyurethanes: 2. Methodology.  Maurice H. George, Helen C. Hailes and David A. Widdowson, J. Chem. Soc., Perkin Trans. 1,  1996, 1395 - 1401.

Chemoenzymatic Resolution and Deracemisation of (±)-1-Methyl-1,2-epoxycyclohexane: the Synthesis of (1-S, 2-S )-1 -Methylcyclohexane-1,2-diol. Ian V.J. Archer, David J. Leak and David A. Widdowson, Tetrahedron Lett., 1996, 37, 8819-8822.

Metal Mediated Synthesis of 4,5-seco-Ergolines. Deirde M.A. Conlon and David A. Widdowson Electronic Conference on Trends in Organic Chemistry  (ECTOC-3), Ed H.S. Rzepa RSC Publications   1996.

Synthesis of Substituted Diaryliodonium Salts and Investigation of their Reactions with No-Carrier-Added [18F]Fluoride. Aneela Shah, David. A. Widdowson, Victor. W. Pike, J. Labelled Compd.Radiopharm., 1997, 40, 65 - 67.

Synthesis of Functionalised Unsymmetrical Diaryliodonium Salts. Aneela Shah,  Victor W. Pike and David A. Widdowson, J. Chem. Soc., Perkin Trans. 1, 1997, 2463 - 2465.

Characterisation of a Catabolic Epoxide Hydrolase from a Corynebacterium  sp. Elisa Misawa, Chan K.C.  Chan Kwo Chion, Ian V. Archer, Marc P. Woodland, Ning-Yi Zhou, Semra F. Carter, David A. Widdowson and David J. Leak, Eur. J. Biochem., 1998, 253, 173 - 183.

The Synthesis of [18F]Fluoroarenes from the Reaction of Cyclotron-produced [18F]Fluoride Ion with Diaryliodonium salts. Aneela Shah, Victor W. Pike and David A . Widdowson, J. Chem. Soc., Perkin Trans. 1, 1998, 2043-2046.

Facile Synthesis of Substituted Diarylidonium Tosylates by Treatment of Aryltributylstannanes with Koser's Reagent. Victor W. Pike, Faisal Butt, Aneela Shah and David A. Widdowson, J. Chem. Soc., Perkin Trans. 1, 1999, 245 - 248.

Fulvene Formation on Attempted Protection of a C2 Symmetric Ferrocenyl Bisphosphine as its Sulfide. Yong-Jin Cho, Michael A. Carroll, Andrew J. P. White, David A. Widdowson and David J. Williams, Tetrahedron Lett., 1999, 40, 8265 - 8268.

Palladium Catalysed Cross-coupling of (Fluoroarene)tricarbonylchromium(0) complexes. David A. Widdowson and René Wilhelm, Chem. Commun., 1999, 2211 - 2212.

An ab initio and MNDO-d SCF-MO Computational Study of Stereoelectronic Control in Extrusion Reactions of R2I-F Iodine(III) Intermediates. Michael A. Carroll, Sonsoles Martín-Santamaría, Victor W. Pike, Henry S. Rzepa and David A. Widdowson, J. Chem. Soc., Perkin Trans. 2, 1999, 2707 - 2714.

Fluoridation of heteroaromatic iodonium salts-experimental evidence supporting theoretical prediction of the selectivity of the process. Sonsoles Martín-Santamaría, Michael A. Carroll, Colm M. Carroll, Charles D. Carter, Victor W. Pike, Henry S. Rzepa annd David A. Widdowson, Chem. Commun., 2000, 649 - 650.

Efficient regio- and diastereo-controlled synthesis of 1,1´- and 1,1´,2,2´- functionalised ferrocenes and the formation of 2-oxa[3]ferrocenophanes. Michael A. Carroll, Andrew J. P. White, David A. Widdowson and David J. Williams, J. Chem. Soc., Perkin Trans. 1, 2000, 1551-1557.

New synthesis of diaryliodonium sulfonates from arylboronic acids. Michael A. Carroll, Victor W. Pike and David A. Widdowson, Tetrahedron Lett., 2000, 41, 5393-5396.

Directed Lithiation in Arenetricarbonylchromium(0) complexes: Assessment of Some Directing Group Specificities and of Electrophilic Quench Efficacies. Iyassu K. Sebhat, Yen-Ling Tan, David A. Widdowson, René Wilhelm, Andrew J.P. White and David J. Williams, Tetrahedron, 2000,  56 , 6121-6134.

Palladium Catalysed Cross-coupling of (Fluoroarene)tricarbonylchromium(0) complexes.  René Wilhelm and David A. Widdowson, J. Chem. Soc., Perkin Trans. 1, 2000, 3808-3813.

An ab initio and MNDO-d SCF–MO computational study of the extrusion reactions of R2I–F iodine(III) via dimeric, trimeric and tetrameric transition states. Sonsoles Martín-Santamaría, Michael A. Carroll, Victor W. Pike, Henry S. Rzepa and David A. Widdowson, J. Chem. Soc., Perkin Trans. 2, 2000, 2158-2161.

Asymmetric deprotonation - substitution of arenetricarbonyl-chromium(0) complexes: substituent controlled lithiation with the butyllithium-sparteine system. René Wilhelm, Iyassu K. Sebhat, Andrew J.P. White, David J. Williams and David A. Widdowson, Tetrahedron: Asymmetry, 2000, 11, 5003-5016.

Expression of benzene dioxygenase from Pseudomonas putida ML2 in cis-1,2-cyclohexanediol-degrading pseudomonads. R.. J. Swift, S. E. Carter, D. A. Widdowson, J. R. Mason and D. J. Leak, App. Microbiol. Biot., 2001, 55, 721-726.

Asymmetric Synthesis of a Fully Protected ent-Actinoidinic Acid. René Wilhelm and David A. Widdowson, Org. Lett., 2001,  3, 3079-3082.

Reversal of Asymmetric Induction in Arenetricarbonylchromium(0) Complexes via Dilithiation with the (–)-Sparteine / BuLi System and Enantioselective Quench. Yen-Ling Tan, David A. Widdowson and René Wilhelm, Synlett, 2001,  1632-1634.

Computational mechanistic studies to rationalize unusual stereo and regiochemical outcomes of extrusion/insertion reactions of iodine (III) and palladium (0) reagents. H.R. Rzepa, S. Martin-Santamaria, D.A. Widdowson, M.A. Carroll and V.W. Pike,  Abstracts of papers of the Americal Chemical Society,  2001, 221, 31.

Dilithiation of arenetricarbonyl(0) complexes with enantioselective quench: application to chiral biaryl synthesis. Y.-L. Tan, A.J.P. White, D.A. Widdowson, R. Wilhelm and D.J. Williams, J. Chem. Soc. Perkin Trans. 1, 2001, 3269-3280.

A Computational Study of the Mechanism of Palladium Insertion into
Alkynyl and Aryl Carbon-Fluorine bonds. Markus Jakt, LinusJohannissen, Henry S. Rzepa, David A. Widdowosn and René Wilhelm, J. Chem.  Soc. Perkin Trans. 2, 2002, 576-581.

Palladium catalysed Suzuki reactions of fluoroarenes. David A. Widdowson and René Wilhelm, Chem. Commun.,  2003, (5), 578-579.

Synthesis and evaluation of two 18F-labelled 6-iodo-2-(4'-N,N-dimethylamino)phenylimidazo[1,2,a]pyridine derivatives as prospective radioligands for ß-amyloid in Alzheimer's disease. Lisheng Cai, Frederick T. Chin, Victor W. Pike, Hiroshi Toyama, Jeih-San Liow, Sami S. Zoghbi, Kendra Modell, Emmanuelle Briard, H. Umesha Shetty, Kathryn Sinclair, Sean Donohue, Dnyanesh Tipre, Mei-Ping Kung, Claudio Dagostin, David A. Widdowson, Michael Green, Weiyi Gao, Mary M. Herman, Masanori Ichise, and Robert B. Innis, J. Med. Chem.,  2004, 47(9), 2208-2218.



Last updated: 25th November 2005