Cytochrome p450

The cytochrome p450 family are a group of over 60 different varieties which act as the bodies most powerful detoxification enzymes. And indeed it is one of this family of enzymes which are responsible for the removal of Sildenafil Citrate from the liver. The family name, p450 describes the characteristic absorption of co at 450nm.

Here we see a cross-section of cytochrome containing vessicles in the liver Below is a representation of the structure of the cytochrome.

 

 

1.Cytochrome p450{short description of image}

I-helix is shown in red.
The haem group is in green.
The yellow regions are the hypervariable regions of the CXP4 family