References

Journals

  • Spande, T. F.; Garraffo, H.M.; Edwards, M.W.; Yeh, H.J.C.; Pannell, L.;Daly, J.W., Epibatidine: a novel (chloropyridyl)-azabicycloheptane with potent analgesic activity from an Ecuadorian poison frog, J. Am. Chem. Soc., 1992, 114, 3475-3478

  • Corey, E.J.; Loh, T.E.; Achyutha-Rao, S.; Daley, D.C.; Sarshar, S., Stereocontrolled Total Synthesis of (+)- and (-)-Epibatidine., J. Org. Chem., 1993, 58, 5600-5602.

  • Huang, D.F.; Shen, T.Y., A Versatile Total Synthesis of Epibatidine and Analogs. Tetrahedron Lett., 1993, 34, 4477-4480.

  • Broka, C.A., Total Synthesis of Epibatidine., Tetrahedron Lett. 1993, 34, 3251-3254.

  • Clayton, S.C.; Regan, A.C., Total Synthesis of (+/-)-Epibatidine., Tetrahedron Lett., 1993, 34, 7493-7496.

  • Aoyagi, S.; Tanaka, R.; Masaichi, N.; Kibayashi, C., Total Synthesis of (-)-Epibatidine Using an Asymmetric Diels-Alder Reaction with a Chiral N-Acylnitroso Dienophile. J. Org. Chem., 1998, 63, 8397-8406.

  • Evans, D.A.; Scheidt, K.A; Downey, C.W, Synthesis of (-)-Epibatidine, Organic Letters, 2001, 3, 3009-3012.

  • Bannon AW., et al., Broad-spectrum non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors., Science, 1998 Jan; 2795(5347): 77-80

Websites

Other

  • Beilstein database

  • NMR predictor

  • Corina

  • John Emsley, Smoke a cig or lick a frog-Epibatidine, Molecules at an Exhibition, page 84, Oxford University Press, 1999

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