Georgios V. Gkoutos, Personal Information

Georgios V. Gkoutos BSc. MSc. Ph.D DIC.

Personal details

Work Adress	Wolfson Laboratory for Informatics, Modelling and Visualisation, Imperial College of Science, Technology & Medicine,Exhibition Road, South Kensington, London SW7 2AY Tel: +44 20 594 5795 Fax: +44 20 594 5804 e-mail: g.gkoutos@ic.ac.uk.
Home Address	128 Roebuck Court, Oxfordshire OX8 11US, UK Tel: +44 1235 814915
Date of Birth	22 June 1976
Current Postion	PostDoc
Nationality	Greek
Marital Status	Single

Ph.D Work

My research was in Chemo/Bioinformatics Internet Resource Discovery , under the supervision of Dr. H. S. Rzepa.

M.Sc. Work

My research was on modelling class A G-Protein Coupled Receptors (GPCRs) and included molecular graphics, correlated mutation and sequence analysis and computer simulations. 6 research articles were published as a result of this work. Part of this project involved studying the role of domain swapping and dimerisation in GPCRs and the role of dimerisation and correlated mutations in MHC class II molecules.

Education Summary

2002-	PostDoctoral Fellow (Supervisor Dr. J. M. Hancock).
1999-2002	Ph.D (Supervisor Dr. H. S. Rzepa).
1997-1999	M.Sc. (Supervisor Prof. C. A. Reynolds).
1994-1997	B.Sc. (honours) degree in Biochemistry, University of Essex.
1993-1994	4 A-level (Maths, Chemistry, Biology, Physics, overall 92%) Interanglian Foundation college, 16 Halkokondili St, Athens, Greece.
1991-1994	12 GCSE equivalents (19^2/12/20) , 1^st Lyceum Upper School, Kifissia, Athens, Greece.
1989-1991	Proficiency in English, University of Cambridge.
1989-1991	First Certificate in German Language, Goethe Institute.

Publications

G. V. Gkoutos, P. Murray-Rust and H. S. Rzepa, Online Transformation and Comparison of Molfile and CML Molecular Atom-Connection Descriptors, New. J. Chem, 2003, 6(1), CP1-U10
G. V. Gkoutos, R. M. Clark, O. A. Adjei and H. S. Rzepa. Chemical Machine Vision Project: Extraction of chemical metadata from raster images, 2002, in press
G. V. Gkoutos, C. Leach and H. S. Rzepa, ChemDig: New approaches to Chemically Significant Indexing and Searching of Distributed Web Collections, New. J. Chem., 2002, 5, 656-666
G. V. Gkoutos, Tools for integration of Web molecular resources, CSA, 2, 2002
G. V. Gkoutos, P. Murray-Rust, H. S. Rzepa, and M. Wright, The Application of XML Languages for Integrating Molecular Resources, Internet J. Chemistry, 2001, 4 (12): U1-U15
G. V. Gkoutos, P. Murray-Rust, H. S. Rzepa and M. Wright, Peer to Peer (P2P) Systems as Molecular Resource Discovery tools, in preparation
G. V. Gkoutos, P. Murray-Rust, H. S. Rzepa and M. Wright, Chemical Markup, XML and the World-Wide Web. Part III: Towards a signed semantic Chemical Web of Trust, J. Chem. Inf. Comp. Sci., 2001, 41 (5): 1124-1130. (Supporting information) http://pubs.acs.org/subscribe/journals/jcisd8/suppi nfo/ci000406v/README.html
P. R. Gouldson, M. K. Dean, C. R. Snell, R.P. Bywater, G. V. Gkoutos and C. A. Reynolds, Lipid facing correlated mutations and dimerization in G-protein coupled receptors, Prot. Engineering, 2001, 14 (10), 759-767
G. V. Gkoutos, P. Murray-Rust, H. S. Rzepa, and M. Wright, Integration of Internet Molecular Resources, CMPTI, 2001, SII1.
G. V. Gkoutos, P. R. Kenway, P. Murray-Rust, H. S. Rzepa and M. Wright, A Resource for Transforming HTML and Molfile Documents to XML Compliant Form, Internet J. Chem., 2001, b (5), U4-U14.
G. V. Gkoutos, P. R. Kenway and H. S. Rzepa, A robot-based resource discovery tool for adding chemical meta-information and value to web-based documents, New. J. Chem., 2001, 25 (4): 635-638
G. V. Gkoutos, P. R. Kenway and H. S. Rzepa, JChemTidy: A Tool for Converting Chemical Web Document Collections to an XHTML Representation., J. Chem. Inf. Comp. Sci., 2001, 41, 253-258
P. R. Gouldson, R. E. Smith, M. K. Dean, C. Higgs, G.V. Gkoutos and C.A. Reynolds, Dimerisation and Domain swapping in GPCRs: a computational approach, Neuropsychopharmacology, 2000, 23, S61-S77.
G. V. Gkoutos and H. S. Rzepa, A Mechanism for Creating Chemically Oriented Internet Search Channels, Internet J. Chem., 2000, 3 (7-8): U9-U19
G. V. Gkoutos, P. R. Kenway and H. S. Rzepa, JChemTidy and JChemDig: New Resource discovery tools for Molecular Sciences, Poster presented at Chemint2000, Washington, September 2000.
G. V. Gkoutos, H. S. Rzepa and M. Wright, Hierarchical display of Chemical Data in Web Browsers, Internet J. Chem., 2000, 3(7-8), U1-U7
G. V. Gkoutos and H. S. Rzepa, Use of Meta-data in Chemical Content Relevancy Ranking, Electronic Conference on Synthesis in Organic Chemistry (ECSOC-2), CD-ROM, Ed. S.-K. Lin and E. Pombo-Villar , 1999. CD-ROM, ISBN 3-906980-01-4 (Publisher MDPI).
G. V. Gkoutos, C. Higgs, R. P. Bywater, P. R. Gouldson, C. A. Reynolds, Evidence for dimerisation in the adrenergic receptor from the evolutionary trace method, Int. J. Quant. Chem., Biophys. Quarterly, 74, 1999, 371-379.
G. V. Gkoutos, R. P. Bywater, C. A. Reynolds and P. R. Gouldson*, Correlated mutation analysis on Neurokinin receptors, prediction on residues that confer subtype specificity, to be submitted to Journal of protein and ion channels * Corresponding author of this article
C. Higgs, G. V. Gkoutos, C. A. Reynolds, A theoretical approach towards understanding the GPCR G-protein interaction, in preparation
A. Nilsson, M. Wijayawardene, G. V. Gkoutos, K. M. Wilson, N. Fernandez and C. A. Reynolds, Correlated mutations in the HLA class II molecule, Int. J. Quant. Chem. Biophy. Quarterly, 73, 1999, 85-96.

Awards & Honours

EPSRC PhD Studentship
Merck Sharp & Dohme funding award
Chemical Structure Association Trust 2001 Award (CSA 2001)
Permission to publish articles in an unchanged format provided in electronic journals (IJC)

Conferences

5^th World Congress of Theoretical Oriented Chemists (WATOC99), London. August 1-6, 1999
Chemistry on the Internet (ChemInt2000), Washington DC. September 23-26, 2000
Computational Methods in Toxicology and Pharmacology Integrating Internet Resources (CMTPI-2001). Centre de Congrés Cité mondiale. Bordeux, France. July 11-13, 2001
International Council on Archives (ICA/SUV), Annual Meeting, London. September 4-7, 2001
Cell Signalling, Transcription and Translation as Therapeutic Targets, Luxembourg. January 30 - February 2, 2002
Developing the European Comprehensive First Line Phenotyping Protocol and the way forward, EUMORPHIA Assembly, Strasbourg. January 15-17, 2003
Open Grid Services Architecture Database Access and Integration, (OGSA-DAI), National eScience Centre, Edinburgh. February 11-12, 2003
Genome Informatics, Cold Spring Harbor Laboratory (CSHL), New York. May 7-11, 2003
Phenotype Ontology, Banbury Conference Centre), New York. May 12-13, 2003
Mouse Behaviour Phenotype, Rome. July 11-12, 2003

Work Experience

3 months industrial placement in MSD (Merck Sharp & Dohme), Neuroscience Research Centre (NRC), under the supervision of Dr. P. R. Kenway.

Hobbies

Tennis and volleyball
Motor racing enthusiast
Reading: thriller novels and 2^nd World War history

Referees

Dr. H.S. Rzepa	Department of Chemistry, Imperial College,London SW7 2AY, UK. e-mail: rzepa@ic.ac.uk Tel: +44 171 794 5774 Fax: +44 171 594 5804 URL: http://www.ch.ic.ac.uk/rzepa
Prof. C. A. Reynolds	Department of Biological Sciences, Central Campus, University of Essex, Colchester, Essex, CO4 3SQ, UK. e-mail: C.A.Reynolds@essex.ac.uk Tel: +44 1206 872540 Fax: +44 1206 872592 URL: http://www.essex.ac.uk/bs/staff/reync/
Dr. P.R. Kenway	Merck Sharp & Dohme, Terlings Park, Harlow, UK. Neuroscience Research Centre (NRC).
Dr. J. R. Miller.	Department of Biological Sciences, Central Campus, University of Essex, Colchester, Essex, CO4 3SQ, UK. e-mail: john@essex.ac.uk Tel: +44 1206 872090 Fax: +44 1206 872592