$Version: 3 $Totobjs: 12 $Pen_RGB2Color: 0 0 0 $Fill_RGB2Color: 0 0 0 $Font: "Arial" 90 1 $Obj: mol $RxnAtch: -1 -1 $Begsketch: $Totobjs: 49 $Obj: atom $Atom_coords: 4732.40137 1028.07275 $Atom_number: 1 $Obj: atom $Atom_coords: 4795.20801 887.71191 $Atom_number: 2 $Obj: atom $Atom_coords: 4946.66748 870.94922 $Atom_number: 3 $Obj: atom $Atom_coords: 5037.05273 995.36450 $Atom_number: 4 $Obj: atom $Atom_coords: 4975.97803 1136.54248 $Atom_number: 5 $Obj: atom $Atom_coords: 4822.78613 1152.48804 $Atom_number: 6 $Obj: bond $Pen_width: 7 $Bond_atoms: 0 5 $Bond_type: double $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 0 1 $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 1 2 $Bond_type: double $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 2 3 $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 3 4 $Bond_type: double $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 4 5 $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 3 15 $Obj: bond $Pen_width: 7 $Bond_atoms: 2 14 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 5010.02930 731.11377 $Atom_alias: "R" $Atom_number: 7 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 5190.79883 979.94409 $Atom_alias: "R" $Atom_number: 8 $Obj: atom $Atom_coords: 4054.00000 1075.00000 $Atom_number: 9 $Obj: atom $Atom_coords: 4054.00000 1229.00000 $Atom_number: 10 $Obj: atom $Atom_coords: 4185.88477 1306.00000 $Atom_number: 11 $Obj: atom $Atom_coords: 4185.88477 998.00000 $Atom_number: 12 $Obj: bond $Pen_width: 7 $Bond_atoms: 16 19 $Bond_type: double $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 16 17 $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 17 18 $Bond_type: double $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 18 25 $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 28 19 $Bond_topo: arom $Obj: atom $Atom_coords: 4319.76904 1229.00000 $Atom_number: 13 $Obj: atom $Atom_coords: 4452.51953 1306.50000 $Atom_number: 14 $Obj: atom $Atom_coords: 4452.51953 998.50000 $Atom_number: 15 $Obj: atom $Atom_coords: 4319.76904 1075.00000 $Atom_number: 16 $Obj: bond $Pen_width: 7 $Bond_atoms: 25 28 $Bond_type: double $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 25 26 $Bond_topo: ring $Obj: bond $Pen_width: 7 $Bond_atoms: 26 43 $Bond_topo: ring $Obj: bond $Pen_width: 7 $Bond_atoms: 42 27 $Bond_topo: ring $Obj: bond $Pen_width: 7 $Bond_atoms: 27 28 $Bond_topo: ring $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 4452.51953 845.50000 $Atom_type: 8 $Atom_number: 17 $Obj: bond $Pen_width: 7 $Bond_atoms: 27 34 $Bond_type: double $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 4452.51953 1459.50000 $Atom_type: 8 $Atom_number: 18 $Obj: bond $Pen_width: 7 $Bond_atoms: 26 36 $Bond_type: double $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 3921.11523 1306.00000 $Atom_alias: "Me^O" $Atom_number: 19 $Obj: bond $Pen_width: 7 $Bond_atoms: 17 38 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 3920.89990 999.37427 $Atom_alias: "Me^O" $Atom_number: 20 $Obj: bond $Pen_width: 7 $Bond_atoms: 16 40 $Obj: atom $Atom_coords: 4586.27051 1075.00000 $Atom_number: 21 $Obj: atom $Atom_coords: 4586.27051 1229.00000 $Atom_number: 22 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 4732.40137 1276.89990 $Atom_type: 8 $Atom_number: 23 $Obj: bond $Pen_width: 7 $Bond_atoms: 0 42 $Bond_topo: ring $Obj: bond $Pen_width: 7 $Bond_atoms: 42 43 $Bond_type: double $Bond_topo: ring $Bond_dbl_side: 2 $Obj: bond $Pen_width: 7 $Bond_atoms: 43 44 $Bond_topo: ring $Obj: bond $Pen_RGB2Color: 255 0 0 $Bond_atoms: 44 5 $Bond_topo: ring $Endsketch: $Obj: mol $RxnAtch: -1 -1 $Begsketch: $Totobjs: 49 $Obj: atom $Atom_coords: 4739.40137 2090.07275 $Atom_number: 1 $Obj: atom $Atom_coords: 4802.20801 1949.71191 $Atom_number: 2 $Obj: atom $Atom_coords: 4953.66748 1933.94922 $Atom_number: 3 $Obj: atom $Atom_coords: 5044.05273 2058.36450 $Atom_number: 4 $Obj: atom $Atom_coords: 4982.97803 2198.54248 $Atom_number: 5 $Obj: atom $Atom_coords: 4829.78613 2214.48804 $Atom_number: 6 $Obj: bond $Pen_width: 7 $Bond_atoms: 0 5 $Bond_type: double $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 0 1 $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 1 2 $Bond_type: double $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 2 3 $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 3 4 $Bond_type: double $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 4 5 $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 3 15 $Obj: bond $Pen_width: 7 $Bond_atoms: 2 14 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 5017.02930 1793.11377 $Atom_alias: "R" $Atom_number: 7 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 5197.79883 2042.94409 $Atom_alias: "R" $Atom_number: 8 $Obj: atom $Atom_coords: 4060.00000 2138.00000 $Atom_number: 9 $Obj: atom $Atom_coords: 4060.00000 2292.00000 $Atom_number: 10 $Obj: atom $Atom_coords: 4192.88477 2368.00000 $Atom_number: 11 $Obj: atom $Atom_coords: 4192.88477 2060.00000 $Atom_number: 12 $Obj: bond $Pen_width: 7 $Bond_atoms: 16 19 $Bond_type: double $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 16 17 $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 17 18 $Bond_type: double $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 18 25 $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 28 19 $Bond_topo: arom $Obj: atom $Atom_coords: 4326.76904 2292.00000 $Atom_number: 13 $Obj: atom $Atom_coords: 4459.51953 2368.50000 $Atom_number: 14 $Obj: atom $Atom_coords: 4459.51953 2060.50000 $Atom_number: 15 $Obj: atom $Atom_coords: 4326.76904 2138.00000 $Atom_number: 16 $Obj: bond $Pen_width: 7 $Bond_atoms: 25 28 $Bond_type: double $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 25 26 $Bond_topo: ring $Obj: bond $Pen_width: 7 $Bond_atoms: 26 42 $Bond_topo: ring $Obj: bond $Pen_width: 7 $Bond_atoms: 41 27 $Bond_topo: ring $Obj: bond $Pen_width: 7 $Bond_atoms: 27 28 $Bond_topo: ring $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 4459.51953 1907.50000 $Atom_type: 8 $Atom_number: 17 $Obj: bond $Pen_width: 7 $Bond_atoms: 27 34 $Bond_type: double $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 4459.51953 2521.50000 $Atom_type: 8 $Atom_number: 18 $Obj: bond $Pen_width: 7 $Bond_atoms: 26 36 $Bond_type: double $Obj: bond $Pen_width: 7 $Bond_atoms: 17 48 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 3927.89990 2061.37427 $Atom_alias: "Me^O" $Atom_number: 20 $Obj: bond $Pen_width: 7 $Bond_atoms: 16 39 $Obj: atom $Atom_coords: 4592.27051 2138.00000 $Atom_number: 21 $Obj: atom $Atom_coords: 4592.27051 2292.00000 $Atom_number: 22 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 4739.40137 2338.89990 $Atom_type: 7 $Atom_number: 23 $Atom_dispflags: 0001 $Atom_hpos: 1 $Obj: bond $Pen_width: 7 $Bond_atoms: 0 41 $Bond_topo: ring $Obj: bond $Pen_width: 7 $Bond_atoms: 41 42 $Bond_type: double $Bond_topo: ring $Bond_dbl_side: 2 $Obj: bond $Pen_RGB2Color: 255 0 0 $Bond_atoms: 42 43 $Bond_topo: ring $Obj: bond $Pen_width: 7 $Bond_atoms: 43 5 $Bond_topo: ring $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 3932.28223 2358.78662 $Atom_alias: "Me^O" $Atom_number: 19 $Endsketch: $Obj: text $Transparent: $Obj_coords: 4421 1603 4478 1723 $MDLEdittext: 0 0011 {\rtf1\defformat\pc {\fonttbl {\f2428\nil Fixedsys;} {\f3244\nil Arial;} {\f2684\nil Arial;} {\f436\nil Arial;} } \plain \f3244\fs20\b 1 } $Obj: text $Transparent: $Obj_coords: 4427 2635 4484 2755 $MDLEdittext: 0 0011 {\rtf1\defformat\pc {\fonttbl {\f3244\nil Arial;} } \plain \f3244\fs20\b 2 } $Obj: mol $RxnAtch: -1 -1 $Begsketch: $Totobjs: 46 $Obj: atom $Atom_coords: 722.00000 1755.00000 $Atom_number: 25 $Obj: atom $Atom_coords: 722.00000 1909.00000 $Atom_number: 26 $Obj: atom $Atom_coords: 854.88452 1986.00000 $Atom_number: 27 $Obj: atom $Atom_coords: 854.88452 1678.00000 $Atom_number: 28 $Obj: bond $Pen_width: 7 $Bond_atoms: 0 3 $Bond_type: double $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 0 1 $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 1 2 $Bond_type: double $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 2 9 $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 10 3 $Bond_topo: arom $Obj: atom $Atom_coords: 987.76904 1909.00000 $Atom_number: 29 $Obj: atom $Atom_coords: 987.76904 1755.00000 $Atom_number: 30 $Obj: bond $Pen_width: 7 $Bond_atoms: 9 10 $Bond_type: double $Bond_topo: arom $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 589.11548 1986.00000 $Atom_alias: "Me^O" $Atom_number: 31 $Obj: bond $Pen_width: 7 $Bond_atoms: 1 12 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 589.89990 1679.37427 $Atom_alias: "Me^O" $Atom_number: 32 $Obj: bond $Pen_width: 7 $Bond_atoms: 0 14 $Obj: atom $Atom_coords: 1120.52905 1986.21533 $Atom_number: 33 $Obj: bond $Pen_width: 7 $Bond_atoms: 9 16 $Obj: atom $Atom_coords: 1120.74438 1679.15735 $Atom_number: 35 $Obj: bond $Pen_width: 7 $Bond_atoms: 10 18 $Obj: atom $Atom_coords: 1252.53809 1755.31458 $Atom_number: 36 $Obj: bond $Pen_width: 7 $Bond_atoms: 18 20 $Obj: bond $Pen_width: 7 $Bond_atoms: 20 23 $Obj: atom $Atom_coords: 1385.00000 1679.00000 $Atom_number: 37 $Obj: atom $Atom_coords: 1518.83118 1755.90186 $Atom_number: 38 $Obj: atom $Atom_coords: 1651.10400 1678.03320 $Atom_number: 39 $Obj: atom $Atom_coords: 1384.44177 1526.22937 $Atom_number: 42 $Obj: bond $Pen_width: 7 $Bond_atoms: 23 26 $Bond_type: double $Obj: bond $Pen_width: 7 $Bond_atoms: 23 24 $Obj: bond $Pen_width: 7 $Bond_atoms: 24 25 $Bond_type: double $Bond_dbl_side: 1 $Obj: bond $Pen_width: 7 $Bond_atoms: 18 33 $Bond_type: double $Obj: bond $Pen_width: 7 $Bond_atoms: 16 32 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 1120.11548 2139.00000 $Atom_alias: "COOMe" $Atom_number: 45 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 1120.51978 1527.50000 $Atom_type: 8 $Atom_number: 46 $Obj: bond $Pen_width: 7 $Bond_atoms: 24 45 $Obj: bond $Pen_width: 7 $Bond_atoms: 40 41 $Bond_type: double $Bond_dbl_side: 2 $Obj: bond $Pen_width: 7 $Bond_atoms: 41 39 $Obj: bond $Pen_width: 7 $Bond_atoms: 40 38 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 1518.19263 1297.16016 $Atom_alias: "R" $Atom_number: 48 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 1784.26306 1449.40259 $Atom_alias: "R" $Atom_number: 49 $Obj: atom $Atom_coords: 1517.71472 1449.36060 $Atom_number: 52 $Obj: atom $Atom_coords: 1650.54590 1525.26245 $Atom_number: 53 $Obj: bond $Pen_width: 7 $Bond_atoms: 26 40 $Obj: atom $Atom_coords: 1650.00000 1677.00000 $Atom_number: 54 $Obj: bond $Pen_width: 7 $Bond_atoms: 41 43 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 1518.51978 1908.50000 $Atom_type: 8 $Atom_alias: "X" $Atom_number: 55 $Endsketch: $Obj: text $Transparent: $Obj_coords: 1053 2251 1110 2371 $MDLEdittext: 0 0011 {\rtf1\defformat\pc {\fonttbl {\f1560\nil Fixedsys;} {\f3244\nil Arial;} {\f3652\nil Arial;} } \plain \f3244\fs20\b 4 } $Obj: text $Transparent: $Obj_coords: 2709 2250 2766 2371 $MDLEdittext: 0 0011 {\rtf1\defformat\pc {\fonttbl {\f3512\nil Fixedsys;} {\f3244\nil Arial;} {\f2960\nil Arial;} } \plain \f3244\fs20\b 5 } $Obj: subsketch $Begsketch: $Totobjs: 4 $Obj: line $ArrowStyle: 1 $Obj_coords: 1958 1773 1756 1774 $Obj: line $ArrowStyle: 1 $Obj_coords: 1803 1747 1696 1803 $Obj: line $ArrowStyle: 1 $Obj_coords: 1704 1803 1810 1859 $Obj: line $ArrowStyle: 1 $Obj_coords: 1960 1829 1758 1830 $Endsketch: $Obj: subsketch $Begsketch: $Totobjs: 4 $Obj: line $ArrowStyle: 1 $Obj_coords: 3719 1189 3539 1332 $Obj: line $ArrowStyle: 1 $Obj_coords: 3599 1323 3466 1349 $Obj: line $ArrowStyle: 1 $Obj_coords: 3472 1343 3526 1219 $Obj: line $ArrowStyle: 1 $Obj_coords: 3681 1138 3501 1280 $Endsketch: $Obj: subsketch $Begsketch: $Totobjs: 4 $Obj: line $ArrowStyle: 1 $Obj_coords: 3693 2168 3513 2025 $Obj: line $ArrowStyle: 1 $Obj_coords: 3574 2035 3439 2009 $Obj: line $ArrowStyle: 1 $Obj_coords: 3445 2014 3500 2139 $Obj: line $ArrowStyle: 1 $Obj_coords: 3655 2219 3475 2077 $Endsketch: $Obj: text $Transparent: $Obj_coords: 1861 2624 3522 2782 $MDLEdittext: 0 0011 {\rtf1\defformat\pc {\fonttbl {\f1964\nil Fixedsys;} {\f3532\nil Arial;} {\f1044\nil Arial;} {\f1992\nil system;} {\f3556\nil Arial;} {\f3100\nil Arial;} {\f1656\nil Arial;} {\f4044\nil Arial;} {\f2660\nil Arial;} } \plain \f4044\fs20\b \m X=H, Br, NO \plain \f2660\fs20\b \dn6 \m 2 \plain \f4044\fs20\b \m ; R=OMe, H } $Obj: mol $RxnAtch: -1 -1 $Begsketch: $Totobjs: 51 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 2201.89990 1661.37427 $Atom_alias: "Me^O" $Atom_number: 66 $Obj: atom $Atom_coords: 2335.00000 1737.00000 $Atom_number: 1 $Obj: atom $Atom_coords: 2335.00000 1891.00000 $Atom_number: 2 $Obj: atom $Atom_coords: 2467.88452 1968.00000 $Atom_number: 3 $Obj: atom $Atom_coords: 2467.88452 1660.00000 $Atom_number: 4 $Obj: bond $Pen_width: 7 $Bond_atoms: 1 4 $Bond_type: double $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 1 2 $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 2 3 $Bond_type: double $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 3 10 $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 15 4 $Bond_topo: arom $Obj: atom $Atom_coords: 2600.76904 1891.00000 $Atom_number: 5 $Obj: atom $Atom_coords: 2734.51978 1968.50000 $Atom_number: 6 $Obj: atom $Atom_coords: 2866.27051 1891.00000 $Atom_number: 7 $Obj: atom $Atom_coords: 2866.27051 1737.00000 $Atom_number: 8 $Obj: atom $Atom_coords: 2734.51978 1660.50000 $Atom_number: 9 $Obj: atom $Atom_coords: 2600.76904 1737.00000 $Atom_number: 10 $Obj: bond $Pen_width: 7 $Bond_atoms: 10 15 $Bond_type: double $Bond_topo: arom $Obj: bond $Pen_width: 7 $Bond_atoms: 10 11 $Bond_topo: ring $Obj: bond $Pen_width: 7 $Bond_atoms: 11 12 $Bond_topo: ring $Obj: bond $Pen_RGB2Color: 255 0 0 $Bond_atoms: 12 13 $Bond_type: double $Bond_topo: ring $Obj: bond $Pen_width: 7 $Bond_atoms: 13 14 $Bond_topo: ring $Obj: bond $Pen_width: 7 $Bond_atoms: 14 15 $Bond_topo: ring $Obj: bond $Pen_width: 7 $Bond_atoms: 13 28 $Obj: bond $Pen_width: 7 $Bond_atoms: 14 49 $Bond_type: double $Obj: bond $Pen_RGB2Color: 255 0 0 $Bond_atoms: 11 48 $Bond_type: double $Obj: bond $Pen_width: 7 $Bond_atoms: 2 47 $Obj: bond $Pen_width: 7 $Bond_atoms: 1 0 $Obj: bond $Pen_width: 7 $Bond_atoms: 12 50 $Obj: atom $Atom_coords: 2998.00000 1659.00000 $Atom_number: 56 $Obj: atom $Atom_coords: 3130.83105 1735.90186 $Atom_number: 57 $Obj: atom $Atom_coords: 3264.10400 1658.03320 $Atom_number: 58 $Obj: atom $Atom_coords: 2997.44165 1506.22937 $Atom_number: 59 $Obj: bond $Pen_width: 7 $Bond_atoms: 28 31 $Bond_type: double $Obj: bond $Pen_width: 7 $Bond_atoms: 28 29 $Obj: bond $Pen_width: 7 $Bond_atoms: 29 30 $Bond_type: double $Bond_dbl_side: 1 $Obj: bond $Pen_width: 7 $Bond_atoms: 29 46 $Obj: bond $Pen_width: 7 $Bond_atoms: 41 42 $Bond_type: double $Bond_dbl_side: 2 $Obj: bond $Pen_width: 7 $Bond_atoms: 42 40 $Obj: bond $Pen_width: 7 $Bond_atoms: 41 39 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 3131.19263 1277.16016 $Atom_alias: "R" $Atom_number: 60 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 3396.26318 1429.40259 $Atom_alias: "R" $Atom_number: 61 $Obj: atom $Atom_coords: 3130.71460 1429.36060 $Atom_number: 62 $Obj: atom $Atom_coords: 3263.54590 1505.26245 $Atom_number: 63 $Obj: bond $Pen_width: 7 $Bond_atoms: 31 41 $Obj: atom $Atom_coords: 3263.00000 1657.00000 $Atom_number: 64 $Obj: bond $Pen_width: 7 $Bond_atoms: 42 44 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 3131.51978 1888.50000 $Atom_type: 8 $Atom_alias: "X" $Atom_number: 65 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 2202.89990 1968.37427 $Atom_alias: "Me^O" $Atom_number: 67 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 2734.51953 2121.50000 $Atom_type: 8 $Atom_number: 68 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 2734.51953 1508.50000 $Atom_type: 8 $Atom_number: 69 $Obj: atom $Font: "Arial" 100 1 $Atom_coords: 2999.51953 1968.50000 $Atom_type: 8 $Atom_number: 70 $Atom_dispflags: 0001 $Endsketch: $Endsketch: