Orena's Team


Mario Orena

Professor of Organic Chemistry
Facoltá di Scienze
Universitá di Ancona
Tel: +39 71 220 4720
Fax: +39 71 220 4714


Silvano Geremia

Researcher of Inorganic Chemistry
Facoltá di Scienze
Universitá di Ancona
Tel: +39 71 220 4416


Roberta Galeazzi

Computational Chemistry Technician
Facoltá di Scienze
Universitá di Ancona
Tel : 39 71 220 4707


Giovanna Mobbili

PhD student
Universitá di Ancona
Tel: +39 71 220 4707


Fields of interest

Selected references

  1. Cardillo, G.; D'Amico, A.; Orena, M.; Sandri, S. "Diastereoselective Alkylation of 3-Acylimidazolin-2-ones: Synthesis of (R)- and (S)-Lavandulol" J. Org. Chem., 1988, 53, 2354.
  2. Cardillo, G.; Orena, M.; Romero, M.; Sandri, S. "Enantioselective Synthesis of 2-Benzyloxyalcohols and 1,2-Diols via Alkylation of Chiral Glycolate Imides. A Convenient Approach to Optically Active Glycerol Derivatives" Tetrahedron, 1989, 45, 1501.
  3. Bongini, A.; Cardillo, G.; Orena, M.; Sabatino, P.; Sandri, S. "New Synthesis of 4,5-Dihydro-1,3-oxazoles and 4,5-Dihydro-1,3-oxazines, Useful Intermediates to Enantiomerically Pure Aminodiols" J. Chem. Soc., Perkin Trans. I, 1990, 3095.
  4. Orena, M.; Porzi, G.; Sandri, S. "A New Approach to 2-Phenylthioalcohols in High Optical Purity" Tetrahedron Lett., 1992, 33, 3797.
  5. Orena. M.; Porzi, G.; Sandri, S. "A New Synthesis of Both Enantiomers of endo-Norborn-5-en-2-ylmethanol" J. Chem. Res., (S), 1992, 42.
  6. Mobbili, G.; Orena, M.; Porzi, G.; Sandri, S. "Synthesis of (+)-Eldanolide, the Sex Pheromone of Eldana saccharina, by Enantioselective Alkylation of a Chiral Imide" J. Chem. Res., (S), 1993, 230.
  7. Cardillo, B.; Galeazzi, R.; Mobbili, G.; Orena, M.; Rossetti, M., "Diastereoselective Hetero-Diels-Alder Cycloaddition of a C-Nitroso Compound Prepared Starting from a Homochiral Imidazolidin-2-one" Tetrahedron: Asymmetry, 1994, 5, 1535.
  8. Cardillo, G.; Orena, M.; Sandri, S.; Tomasini, C., "An Efficient Synthesis of (R)-(+)- and (S)-(-)-Propranolol from Resolved 5-Iodomethyloxazolidin-2-ones" Tetrahedron, 1987, 43, 2505.
  9. Bongini, A.; Cardillo, G.; Orena, M.; Porzi, G.; Sandri, S.; "A New Synthesis of Both the Enantiomers of 4-Amino-3-hydroxybutanoic Acid (GABOB) and MM2 Calculations for Rotamers of the Intermediate Oxazolidin-2-ones" Tetrahedron, 1987, 43, 4377.
  10. Bongini, A.; Cardillo, G.; Orena, M.; Porzi, G.; Sandri, S., "Synthesis of Aminoalcohols via Perihydro-1,3-oxazin-2-ones and Absolute Configuration Assignment through MM2 Calculation" Chem. Lett., 1988, 87.
  11. Bruni, E.; Cardillo, G.; Orena, M.; Sandri, S.; Tomasini, C., "Synthesis of Chiral 1,2-Diamines" Tetrahedron Lett., 1989, 30, 1679.
  12. Orena, M.; Porzi, G.; Sandri, S., "A New Synthesis of (R)-GABOB and (R)-Oxiracetam" J. Chem. Res., (S), 1990, 376; (M), 1990, 2701.
  13. Cardillo, G.; Orena, M.; Penna, M.; Sandri, S.; Tomasini, C., "Synthesis of (R)-N-Tosylemeriamine via Chiral N-Tosylimidazolidin-2-ones" Synlett, 1990, 543.
  14. Cardillo, G.; Orena, M.; Penna, M.; Sandri, S.; Tomasini, "A New Approach to the Synthesis of Enantiomerically Pure 2,3-Diaminoacids through Chiral Imidazolidin-2-ones" C., Tetrahedron, 1991, 47, 2263.
  15. Orena, M.; Porzi, G.; Sandri, S., "Diastereoselective Alkylation of (3S)- and (3R)-Methylpiperazin-2,5-dione Derivatives. A Convenient Approach to Both (S)- and (R)-Alanine" J. Org. Chem., 1992, 57, 6532.
  16. Orena, M.; Porzi, G.; Sandri, S., "(3R)- and (3S)-Methylpiperazine-2,5-dione Derivatives as Useful Intermediates in the Enantioselective Synthesis of [a]-Amino Esters" J. Chem. Res., (S), 1993, 318; (M), 1993, 2125.
  17. Cardillo, B.; Galeazzi, R.; Mobbili, G.; Orena, M.; Rossetti, M., "Synthesis and Structural Assignment of Diastereomerically Pure N-Substituted 4-Alkylpyrrolidin-2-ones, Intermediates for the Preparation of 3-Alkylpyrrolidines in Both Enantiomerically Pure Forms" Heterocycles, 1994, 38, 2663.
  18. Cardillo, B.; Galeazzi, R.; Mobbili, G.; Orena, M.; "Cyclization of a Chiral N-Crotyl Methoxycarbonylacetamide Mediated by MnIII. An Easy Entry to (R)-3-Pyrrolidineacetic Acid" Synlett, 1995, 11, 1159.
  19. Galeazzi, R.; Geremia S., Mobbili, G.; Orena, M.; "Diastereomerically Pure Pyrrolidin-2-ones by Intramolecular Michael Reaction. Synthesis of Both (S)- and (R)-3-Pyrrolidineacetic Acid." Tetrahedron: Asimmetry, 1996, 7, 79.
  20. Galeazzi, R.; Mobbili, G.; Orena, M.; "A Convenient Approach to Diasteremerically Pure 1,3,4-Trisubstituted Pyrrolidin-2-ones by Intramolecular Cyclisation of N-(Alk-2-en-1-yl)amides Mediated by MnIII. An Entry to Both (R)- and (S)-3-Pyrrolidinacetic Acid." Tetrahedron, 1996, 52, 1069.