ECHET96 Article 055:

John Lyga (
Wed, 10 Jul 1996 12:29:23 -0500

I have a few questions about your synthesis of
5-aryl-2-aminopyrazines. Can these be made using
arylboronates in place of the stananes? Your paper shows
several aryl examples having unsubstituted or para
substituted rings, how does the coupling reaction work with
an ortho substituent? Also, have you tried any other
chemistry on the 2-amino group such as Sandmeyer reactions?
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