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Chris Braddock read Chemistry at St Peter's College, Oxford and graduated with first class honours in 1992. He remained in Oxford to work with John Brown, FRS, for his doctorate which he obtained in January 1996. He was immediately appointed as a Fixed-Term Lecturer at Imperial College where he worked in Professor Tony Barrett's laboratories. In October 1998 he was appointed as a Lecturer in the newly created Synthesis section in the Department of Chemistry and initiated independent research. He was promoted to Senior Lecturer in 2005, to Reader in 2008, and to Professor of Organic Chemistry in September 2015.

He was the winner of the Specialised Organic Chemicals Sector Association (SOCSA) 2000 Innovation Prize, the Royal Society of Chemistry Green Chemistry Jerwood Salters' Environment Award 2000, the Institute of Applied Catalysis (iAc) Award 2001 and the Pfizer award for teaching excellence 2002. He was awarded a Faculty of Natural Sciences Award for Excellence in Teaching 2012, FoNS, Imperial College London, 2012, a Rector's Prize for Excellence in Teaching 2012, Imperial College London, 2012 and the President's award for excellence in Pastoral Care 2014, Imperial College London, 2014. He was admitted to Fellow FRSC (Fellow of the Royal Society of Chemistry) in September 2014, and was the recipient of a Thieme Chemistry Journal award in 2015.